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Pityriasis versicolor: an update on pharmacological treatment options
Introduction: Pityriasis versicolor (PV) is a superficial fungal infection caused by Malassezia species; a yeast that naturally colonizes on the skins surface. High efficacy rates Expert Option 模拟账户 are generally obtained with both topical and systemic treatments. However, recurrence rates following successful treatment remain high and there are no dosage guidelines available for administration of systemic antifungal agents that carry risks of adverse events.
Areas covered: This review focused on providing an overview of existing treatments for PV and an introduction to new treatments. A literature search was conducted using the search strategy, pityriasis versicolor OR tinea versicolor. Over the past decade, few new treatments have been introduced, but the efficacy and the dosing regimens of existing treatments have been systematically reviewed. The results of these reviews are discussed.
Expert opinion: Existing topical and systemic agents are both effective treatments against PV. Previous dosage recommendations for systemic agents have been modified based on recent evidence elucidated in systematic reviews. However, the absence of standardized collection and reporting practices in clinical trials precludes any conclusions to be drawn regarding the efficacy and safety of topical and systemic agents in comparison or in concert with each other.
Keywords: pityriasis versicolor; systemic antifungal; tinea versicolor; topical antifungal; treatment.
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Kallini JR, Riaz F, Khachemoune A. Kallini JR, et al. Int J Dermatol. 2014 Feb;53(2):137-41. doi: 10.1111/ijd.12345. Epub 2013 Dec 10. Int J Dermatol. 2014. PMID: 24320140 Review.
Gupta AK, Bluhm R, Summerbell R. Gupta AK, et al. J Eur Acad Dermatol Venereol. 2002 Jan;16(1):19-33. doi: 10.Expert Option 模拟账户 1046/j.1468-3083.2002.00378.x. J Eur Acad Dermatol Venereol. 2002. PMID: 11952286 Review.
Cantrell WC, Elewksi BE. Cantrell WC, et al. J Drugs Dermatol. 2014 Jul;13(7):855-9. J Drugs Dermatol. 2014. PMID: 25007370 Clinical Trial.
Hobi S, Cafarchia C, Romano V, Barrs VR. Hobi S, et al. J Fungi (Basel). 2022 Jul 4;8(7):708. doi: 10.3390/jof8070708. J Fungi (Basel). 2022. PMID: 35887463 Free PMC article. Review.
Georgescu SR, Mitran CI, Mitran MI, Matei C, Popa GL, Erel O, Tampa M. Georgescu SR, et al. J Clin Med. 2022 Mar 9;11(6):1507. doi: 10.3390/jcm11061507. J Clin Med. 2022. PMID: 35329832 Free PMC article. Review.
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